منابع مشابه
Fibrinogen-binding proteins of Gram-positive bacteria.
Fibrinogen (Fg), the major clotting protein in blood plasma, plays key roles in blood coagulation and thrombosis. In addition, this 340 kD glycoprotein is a stress inducible protein; its synthesis is dramatically upregulated during inflammation or under exposure to stress such systemic infections. This regulation of Fg expression indicates that Fg also participates in the host defense system ag...
متن کاملNovel surface display system for proteins on non-genetically modified gram-positive bacteria.
A novel display system is described that allows highly efficient immobilization of heterologous proteins on bacterial surfaces in applications for which the use of genetically modified bacteria is less desirable. This system is based on nonliving and non-genetically modified gram-positive bacterial cells, designated gram-positive enhancer matrix (GEM) particles, which are used as substrates to ...
متن کاملQnr-like pentapeptide repeat proteins in gram-positive bacteria.
OBJECTIVES To study the role of Qnr-like pentapeptide repeat proteins (PRPs) from several gram-positive species with quinolone resistance in vitro. METHODS A PCR-based strategy was used to clone and express genes coding for Qnr-like PRPs in Enterococcus faecalis, Enterococcus faecium, Listeria monocytogenes, Clostridium perfringens, C. difficile, Bacillus cereus and B. subtilis in Escherichia...
متن کاملSurface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope.
The cell wall envelope of gram-positive bacteria is a macromolecular, exoskeletal organelle that is assembled and turned over at designated sites. The cell wall also functions as a surface organelle that allows gram-positive pathogens to interact with their environment, in particular the tissues of the infected host. All of these functions require that surface proteins and enzymes be properly t...
متن کاملProtein secretion and surface display in Gram-positive bacteria
The cell wall peptidoglycan of Gram-positive bacteria functions as a surface organelle for the transport and assembly of proteins that interact with the environment, in particular, the tissues of an infected host. Signal peptide-bearing precursor proteins are secreted across the plasma membrane of Gram-positive bacteria. Some precursors carry C-terminal sorting signals with unique sequence moti...
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ژورنال
عنوان ژورنال: Microbiology Spectrum
سال: 2019
ISSN: 2165-0497
DOI: 10.1128/microbiolspec.gpp3-0012-2018